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Vaccinations for Prevention of Infectious Respiratory Conditions in Performance Horses
Species

Equine

Contact Hours

3 Hours

Early Booking Deadline

Thu, 01 January, 1970

Registration Deadline

Thu, 01 January, 1970

Language

English

Discipline

Internal Medicine – Endocrinology, Haematology, Infectious Diseases, Parasitology & Oncology

Pathology - Clinical & Gross

Sports Medicine

Industry Partners

Global

Veterinary Partners

Global

Recorded on: 23rd August 2022
                                                  

Panelists:

Romain Paillot   DEPHE, PhD, HMR  - Writtle University College, UK
Nicola Pusterla  Dr.Med.Vet., PhD, DACVIM – UC Davis, USA
Elizabeth Davies    DVM, PhD, DACVIM - Kansas State University’s College of Veterinary Medicine, USA

Moderator:

Julia Kydd PhD - Western College of Veterinary Medicine, Canada

 

CONTENT DESCRIPTION

Combined with efficient biosecurity and infection control measures, vaccination against equine infectious respiratory pathogens is a powerful tool to limit the severity of disease in individuals and groups of horses. Vaccination against selected pathogens is often mandatory in performance horses competing in affiliated events. Several vaccines are available to combat diseases caused by respiratory viruses or bacteria. The main products provide some clinical protection against disease arising after infection with equine influenza virus, equine herpesvirus-1 (including respiratory disease and equine herpesvirus abortion) and Streptococcus equi equi, but to varying degrees.

An international panel of world-renowned equine internists and researchers will provide a brief overview on each pathogen and outline how knowledge of the pathogenesis and protective immune responses against a specific pathogen contribute to vaccine design. The challenges associated with effective vaccination across the equine industry, particularly in performance horses will be highlighted. The concepts underlying the regulatory requirements for selected vaccines will be explored, together with consideration of the factors that may have an impact on the efficacy of vaccines and disease transmission in performance horses.

Elizabeth Davis, DVM, PhD, Dipl. ACVIM, is an associate professor and section head of equine medicine and surgery at Kansas State University’s College of Veterinary Medicine. Her research focuses on immunology and effective vaccination strategies and clinical pharmacology. She is co-director of the NIH-Merial Veterinary Research Scholars program.

Janet obtained a degree from the University of Leeds, UK and went on to study part-time for a PhD on antigenic and genetic variation among equine H3N8 influenza A viruses at the Animal Health Trust, Newmarket, UK. After completing her PhD in 1996, she worked at the National Institute for Biological Standards and Control investigating the safety and efficacy of influenza DNA vaccines followed by Glaxo SmithKline developing the influenza antiviral zanamivir (Relenza) before returning to the Animal Health Trust for a further 5 years. While at the Animal Health Trust, she conducted numerous vaccine efficacy studies on behalf of vaccine manufacturers. After a brief period at the University of Liverpool studying flaviviruses, she worked as a medical writer for a year. She has been at the University of Nottingham’s School of Veterinary Medicine and Science since 2009 where she is currently Professor of Viral Zoonoses, lead of the One Virology group and deputy director of the Wolfson Centre for Global Virus Research. She has ongoing projects to develop improved vaccines against different viral diseases including equine influenza and African horse sickness.

Julia graduated with degrees in Zoology and Equine Science from the Universities of Dundee and Aberystwyth respectively. These laid the foundations for a career in equine research involving reproduction and viral respiratory disease. Her first employment as a research assistant at the Thoroughbred Breeders’ Association, Equine Fertility Unit developed her interest in equine embryo transfer which then deepened into the mare’s immune response to pregnancy. This led to a PhD qualification from the University of Cambridge, supervised by the late Professor W.R. (Twink) Allen and Professor Doug Antczak (Cornell University). After 10 years, a post-doctoral role at the Animal Health Trust, Newmarket with Professor Duncan Hannant focussed on the equine immune response to equine herpesvirus-1 with a view to improving current vaccines. This led to the publication of scientific papers in peer reviewed journals and the organisation of international workshops which focussed on this virus. In 2006, a transition into an academic role, including the establishment of a new veterinary school in Nottingham enhanced Julia’s skills in curriculum design, teaching, assessment and pastoral support. Julia is currently a member of the International Committee which organises the International Equine Infectious Disease Conferences and Secretary to the International Equine Reproduction Symposium. In retirement, Julia retains an active interest in equine infectious disease research.  

Dr. Pusterla is currently a professor in Equine Internal Medicine at UC Davis and chief of the large animal medicine services at the William R. Pritchard Veterinary Medical Teaching Hospital. He graduated from the School of Veterinary Medicine at the University of Zurich, Switzerland in 1991 and earned his PhD from the University of Zurich with an emphasis on vector-borne diseases. He joined UC Davis in 1998. Dr. Pusterla is a Diplomate of the American College of Veterinary Internal Medicine with an equine emphasis and has ongoing interest in all aspects of equine internal medicine and dentistry.

As a Principal Investigator, my main research focused on immunity and respiratory pathogens (mainly in equids, but also in other veterinary species). My work aimed to improve our understanding of immunity induced by the pathogens during infection and by vaccination and to elucidate specific mechanisms used by pathogens to evade or deregulate the immune response. I have been strongly involved with veterinary vaccine manufacturers, as Study Investigator, in the evaluation of equine vaccines. I have also trained and mentored numerous undergraduate and post-graduate students, and provided University lectures in biological sciences, such as immunology, infectiology and vaccinology. I am now a Senior Lecturer at Writtle University College, which allows me to share my passion for veterinary sciences with the next generation of research associates and scientists.

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